no one 和none都表示“沒有”，但是用法上有很多區别：
1、none既可指人也可指物，反義詞是all；而no one隻可以指人，如：
None of us knew how to treat her.
我們沒有人知道該如何對待她。（指人）
She did none of the maintenance on the vehicle itself.
她對車子本身沒有進行半點養護。（指物）
No one can open mail except the person to whom it has been addressed.
除收信人本人外，沒人能打開郵件。（指人）
2、none與of連用修飾名詞複數或代詞賓格複數作主語,謂語動詞既可用單數也可用複數，多用單數；而no one不能與of連用。如：
None of us knew how to treat her.
我們沒有人知道該如何對待她。
3、none可一般用來回答how many +n,how much +n 及含any+n引起的疑問句；而no one可回答來回答who,及含anyone,anybody引起的疑問句，如：
—How many books are there on the desk?—None.桌子上有幾本書?一本也沒有。
—Who is in that room?—No one.誰在房間裡？沒有人。
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